New anesthesia drug aims to make kidney stone surgery less painful
NCT ID NCT07659132
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compares a newer anesthesia drug, fospropofol disodium, with the standard drug propofol for people undergoing ureteroscopy (a procedure to remove kidney stones). About 190 adults will be randomly assigned to receive one of the two drugs during surgery. The main goal is to see which drug leads to higher patient satisfaction 24 hours after the procedure, and to check for side effects like injection pain or heart issues.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- fospropofol disodium
- What this could lead to
- If fospropofol works better, it could offer a smoother anesthesia experience with less injection pain for people having ureteroscopy.
- What could go wrong
- This is a small, single-center trial that hasn't started yet. Results may not apply to other surgeries or populations, and fospropofol may not prove superior.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 190 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Undergoing elective ureteroscopic surgery * Aged between 18 and 90 years old * American Society of Anesthesiologists (ASA) physical status classification grade I to III Exclusion Criteria: * Known allergy to propofol, fospropofol or their excipients * Severe cardiopulmonary insufficiency * Hepatic and renal dysfunction.Hepatic or renal insufficiency. Hepatic dysfunction: alanine aminotransferase (ALT) \> 50 U/L, or aspartate aminotransferase (AST) \> 40 U/L, or total bilirubin (TBIL) ≥ 19 μmol/L; Renal dysfunction: serum creatinine (Cr) \> 112 μmol/L, or blood urea nitrogen (BUN) \> 7.1 mmol/L, or receiving dialysis within 28 days before surgery. * Pregnancy, lactation, potential pregnancy or planned pregnancy * Subjects who refuse to participate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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