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Rest between sets: the secret to stronger workouts without the pain?

NCT ID NCT07679971

Knowledge-focused Sponsor: Federal University of Vicosa Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 01, 2026 · Last updated Sep 11, 2026 · Updated 2 times

Summary

This study looks at how different rest intervals between sets of flywheel resistance exercise affect muscle damage and performance in men who haven't done strength training in the last six months. Participants do a single session of lower-body exercises with either 1, 2, or 3 minutes of rest between sets. Researchers measure changes in muscle strength, soreness, swelling, and blood markers over several days to see which rest period leads to the best recovery and performance.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
flywheel resistance exercise with varying inter-set rest intervals
What this could lead to
If successful, this study could help design more effective and safer resistance training programs by identifying optimal rest intervals to minimize muscle damage while maximizing performance.
What could go wrong
This is a small, early-stage study in untrained men only, so results may not apply to women, trained individuals, or other exercise types. The outcomes are indirect markers of muscle damage, not direct measures of injury or recovery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 40 years; * Apparently healthy and clinically able to perform physical exercise; * No participation in structured resistance training during the previous 6 months; * Agreement to comply with all study visits and procedures; * Signed informed consent form. Exclusion Criteria: * History of lower-limb musculoskeletal injury or surgery that may impair performance or safety during the proposed exercise protocol; * Current pain, injury, or functional limitation in the lower limbs; * Use of ergogenic aids that may affect physical performance or muscle recovery; * Use of analgesic or anti-inflammatory medication during the study period; * Failure to attend the scheduled visits required for the primary outcome assessment.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Exercise induced muscle damage

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Federal University of Viçosa

    RECRUITING

    Viçosa, Minas Gerais, 36570-900, Brazil

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