Antidepressant may boost vision in lazy eye
NCT ID NCT07417046
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether adding fluoxetine (a common antidepressant) to standard eye patching can improve and maintain vision in people over 10 with lazy eye (amblyopia). Researchers will use special eye scans and brain tests to measure changes. The goal is to find a new way to treat lazy eye in older children and adults.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2024
- Expected to finish
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Apr 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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10 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with unilateral amblyopia \> 10 years old. Exclusion Criteria: * Ocular pathology: media opacity, uveitis, glaucoma, retinal or optic nerve diseases, and history of ocular trauma. * Poor fixation. * Lack of cooperation. * Any psychological disorder.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of medicine, Minia university
RECRUITINGMinya, Minya Governorate, 61511, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Mixed-Reality headset trains eyes to work together in adults with lazy eye
- A new exercise for the eyes: could it restore 3D vision?
- Video games vs eye patches: a new hope for lazy eye?
- Adult lazy eye may be trainable: brain plasticity under the microscope
- Can a gentle brain zap help adults with lazy eye see better?
- Magnetic pulses to the brain may restore vision in adult lazy eye