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New device aims to suck out dangerous lung clots

NCT ID NCT05560763

First seen Sep 30, 2025

Summary

This study tested a device called the FlowTriever2 Catheter in 50 people with acute pulmonary embolism (blood clots in the lungs). The catheter is threaded through a blood vessel to mechanically break up and remove the clot. Researchers measured safety by tracking serious complications like major bleeding or death within 48 hours, and effectiveness by checking if blood pressure in the lungs improved after the procedure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baptist Health

    Louisville, Kentucky, 40207, United States

  • Carondelet St. Joseph's Hospital

    Tucson, Arizona, 85711, United States

  • Memorial Health University Medical Center

    Savannah, Georgia, 31404, United States

  • Oklahoma Heart Institute

    Tulsa, Oklahoma, 74104, United States

  • University of Tennessee Medical Center

    Knoxville, Tennessee, 37920, United States

  • Virtua Health

    Camden, New Jersey, 08103, United States

  • Yale University

    New Haven, Connecticut, 06511, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

FlowTriever2 Catheter (a device used to mechanically remove blood clots from the pulmonary arteries)

What this could lead to

If successful, this could provide a safe and effective way to quickly remove large blood clots from the lungs, potentially improving breathing and heart function in people with pulmonary embolism.

What could go wrong

This was a small, single-arm study with only 50 participants, so results may not apply to everyone. There are risks of bleeding, vessel injury, or worsening condition during the procedure.

Conditions

The condition(s) this trial relates to.

pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.