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Vaginal gel may cut repeat UTIs in menopause

NCT ID NCT05573334

First seen Jan 31, 2026 · Last updated Jun 22, 2026 · Updated 29 times

Summary

This completed study tested whether an over-the-counter vaginal care system (Flourish HEC) could lower the number of urinary tract infections in menopausal women who get them often. The idea is that the gel helps restore a healthy vaginal microbiome, which may protect against UTIs. Only 8 women took part, so the results are very preliminary.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Center for Urogynecology & Pelvic Reconstructive Surgery

    Newark, Delaware, 19713, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vaginal moisturizing gel (BioNourish) as part of a hygiene system

What this could lead to

If it works, this could offer a non-hormonal, over-the-counter option to help menopausal women reduce recurrent urinary tract infections.

What could go wrong

This was a very small study (8 participants) with no phase designation, so results may not be reliable or generalizable. The device is already on the market, but its effectiveness for UTI prevention is unproven.

Conditions

The condition(s) this trial relates to.

urinary tract infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.