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Dental implant showdown: titanium mesh vs collagen membrane for stronger smiles

NCT ID NCT06875830

Disease control Sponsor: Misr International University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jul 07, 2026 · Updated 3 times

Summary

This study tests two ways to rebuild bone around dental implants placed right after tooth extraction in the upper front area. Twenty adults with broken upper premolars will get either a titanium mesh or a collagen membrane, both with bone graft material. The main goal is to see which method gives thicker bone on the cheek side, measured by 3D X-ray. Results could help dentists choose the best technique for lasting implant success.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
titanium mesh and collagen membrane (used with xenograft for bone augmentation)
What this could lead to
If successful, this could show that titanium mesh is better than collagen membrane for preserving bone thickness around dental implants, improving long-term implant stability.
What could go wrong
This is a very small early-stage trial with only 20 participants, so results may not apply to everyone. The procedures are surgical, with risks like infection or implant failure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2025

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients who have at least one remaining root or badly decayed tooth in anterior maxilla. 2. Systemically free patients (American Society of Anesthesiologists I; ASA I) 3. Patients aged from 21 to 50 years old 4. Buccal bone partial deficiency (extraction socket type II) 5. Good oral hygiene 6. Accepts the follow-up period (cooperative patients) 7. Patient accepts to provides an informed consent Exclusion Criteria: 1. Patients with habits that may jeopardize the implant longevity and affect the results of the study such as parafunctional habits such as bruxism 2. Smokers 3. Pregnant and lactating females

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Badly broken maxillary premolars indicated for extraction Bone augmentation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of oral & dental Medicine,Misr international University

    RECRUITING

    Cairo, Heliopolis - Cairo, 123456, Egypt

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