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Fibromyalgia's hidden impact on eye blood flow revealed?

NCT ID NCT07345546

Knowledge-focused Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study examined whether fibromyalgia, a condition causing widespread pain, is linked to changes in eye blood vessels. Researchers compared 80 people with and without fibromyalgia using eye scans and symptom questionnaires. The goal was to see if nerve system problems in fibromyalgia affect eye circulation, which could help understand the condition better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors understand how fibromyalgia affects the body beyond pain, possibly leading to new ways to monitor the condition.
What could go wrong
This is a small, completed observational study, not a treatment trial. It only looks for a link, not a cause, and results may not apply to everyone with fibromyalgia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

80 people

The number who actually took part.

Started

Oct 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults aged 18-50 years with fibromyalgia and matched healthy controls recruited from Prof. Dr. Cemil Taşcıoğlu City Hospital in Istanbul, Turkey.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-50 years, female or male * Fibromyalgia group: diagnosis of fibromyalgia according to 2016 ACR criteria * Ability and willingness to provide written informed consent * Adequate ocular media clarity suitable for OCT imaging * Control group: age- and sex-matched healthy volunteers Exclusion Criteria: * Ocular exclusions: cataract or other media opacity; glaucoma or optic nerve disease; ocular surface disorders (e.g., dry eye disease); retinal diseases (e.g., diabetic retinopathy, macular disease); ocular surgery or eye/head trauma within the last 3 months; best-corrected visual acuity \< 20/20; refractive error \> ±3.00 diopters; intraocular pressure \> 21 mmHg; use of topical ophthalmic medications * Systemic/neurologic exclusions: diabetes mellitus; hypertension; hyperlipidemia; thyroid disorders; inflammatory rheumatic/autoimmune diseases; polyneuropathy or neurodegenerative disease; major depressive disorder or anxiety disorder; heavy smoking (\>20 cigarettes/day); alcohol or substance dependence; excessive caffeine intake (\>2.5 cups/day)

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Conditions

The condition(s) this trial relates to.

fibromyalgia primary dysautonomia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Autonomic dysfunction Fibromyalgia

Contacts and locations

Locations

  • Prof. Dr. Cemil Taşçıoğlu Şehir Hastanesi

    Istanbul, Istanbul, Turkey (Türkiye)

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