Non-Invasive heart scan could spare patients from risky catheter procedure
NCT ID NCT06790836
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a special CT scan (FFR CT) can accurately measure blood flow in the heart's arteries compared to the standard invasive test. Researchers will review data from 500 patients with suspected coronary artery disease. If FFR CT proves accurate, it could reduce the need for invasive procedures, lowering risks and costs.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could support using a non-invasive CT scan instead of an invasive catheter procedure to diagnose blocked heart arteries, making diagnosis safer and cheaper.
- What could go wrong
- This is a retrospective study looking at past data, not a controlled trial. It can show correlation but cannot prove that FFR CT works better than standard care. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The existing CTCA database for patients treated at Sandwell and West Birmingham NHS Trust between January 1, 2019, and December 31, 2023, with the clinical team screening the database to identify patients who fit with the eligibility criteria.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * •≥18 years * Stable •patients with suspected CAD * Patients who underwent CTCA, FFR CT and had an invasive FFR. * CTCA images of high-quality for analysis, with clear visualisation of coronary arteries and minimal artifacts. Exclusion Criteria: * •\<18 years of age * Did not undergo FFR CT * Inadequate quality/degraded CTCA images
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sandwell and West Birmingham NHS Trust
RECRUITINGBirmingham, West Midlands, B71 4HJ, United Kingdom
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