Cold sponging or just meds? new study tests best way to lower Kids' fevers
NCT ID NCT07426744
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether adding cold sponging to standard fever medicine (paracetamol) helps children cool down faster. About 210 children aged 6 months to 5 years with a fever will be split into two groups: one gets medicine only, the other gets medicine plus cold sponging. The main goal is to see if the combination brings fever below 38°C within 60 minutes more effectively.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 210 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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6 to 60 months
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children of either gender * Aged 6 to 60 months. * Presenting with a fever (an axillary or oral temperature \>38.0°C) * No use of paracetamol or other antipyretics within the past 6 hours. 4. Parental/guardian giving informed written consent. Exclusion Criteria: * Children with chronic systematic conditions (e.g., congenital heart defects, renal or respiratory diseases) * History of febrile seizures or other seizure disorders * Known hypersensitivity or contraindication to paracetamol * Presence of dermatological conditions that may aggravate by sponging (eg., eczema, contact dermatitis, psoriasis, skin infection, xerosis)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Dr. Ruth KM Pfau Civil Hospital, Karachi, Dow University of Health Sciences
Karachi, Sindh, 74400, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could letting fever run its course help brain injury patients?
- New dissolving paracetamol tablet put to the test
- Blood test may spot hidden infections in sick kids