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Blood test may spot hidden infections in sick kids

NCT ID NCT01175005

Knowledge-focused Sponsor: Phoenix Children's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a blood marker called procalcitonin can help doctors quickly identify serious bacterial infections in children with fever and a central line (a tube placed in a large vein). The study included 62 children up to age 18 who came to the emergency department with fever and a central line, often due to cancer or other serious illnesses. Researchers measured procalcitonin levels and tracked whether patients had a bloodstream infection, aiming to find a cutoff level that signals high risk. The goal was to improve early detection and treatment of dangerous infections in this vulnerable group.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

62 people

The number who actually took part.

Start date

May 2010

Finished

Sep 2010

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with fever and a central venous catheter who are 18 years of age and younger will be enrolled and will have PCT levels drawn in the Emergency Department.

Ages

Up to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 years of age and younger * Fever and a central venous catheter * Presentation to an Emergency Department * Central line secondary to Hematologic/Oncologic, Renal or Gastrointestinal disease Exclusion Criteria: * Intravenous antibiotics in the 24 hours prior to presentation * PICC line * Parental refusal or inability to provide consent

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Conditions

The condition(s) this trial relates to.

Fever

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Fever

More trials for these conditions

Other studies related to the condition(s) this trial covers.