Study aims to find best surgery to preserve fertility in cervical cancer patients
NCT ID NCT07394413
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study reviews past research and hospital data to compare three types of fertility-sparing surgeries for cervical adenocarcinoma: conization, simple trachelectomy, and radical trachelectomy. The goal is to see which offers the best balance between controlling cancer and allowing future pregnancy. Researchers will look at recurrence rates, survival, and pregnancy outcomes in 100 women.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors choose the best fertility-sparing surgery for cervical adenocarcinoma, balancing cancer control with the chance of having a baby.
- What could go wrong
- This is a review of existing data, not a new treatment trial. It may not provide definitive answers due to differences in past studies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult women of reproductive age with cervical adenocarcinoma undergoing fertility-sparing surgery (conization, simple trachelectomy, radical trachelectomy) between 01/06/2019 and 30/06/2024
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult women of reproductive age with a diagnosis of cervical adenocarcinoma * Undergoing fertility-sparing surgery * Minimum 12-month follow-up * Signed informed consent Exclusion Criteria: * Histotypes other than cervical adenocarcinoma * Undergoing radical surgery * Follow-up less than 12 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Roma, 00100, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a higher radiation dose beat cervical cancer without more harm?
- Can adding radiation boost the power of immunotherapy in advanced cervical cancer?
- New smart chemo targets tumors, spares healthy tissue
- Prehabilitation boosts pelvic floor recovery in cervical cancer patients
- Gene-Guided drug cocktail shows promise for Tough-to-Treat gynaecological cancers