New fertility library aims to unlock secrets of unexplained infertility
NCT ID NCT05599724
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aimed to create a library of biological samples and clinical data from 250 women with unexplained infertility or low ovarian reserve. Researchers collected blood, DNA, vaginal swabs, and fluid from egg retrieval to help future studies find markers that predict pregnancy success with IVF. The study was terminated early, so the library may be incomplete.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this library could help researchers find new biomarkers to predict which women with unexplained infertility are most likely to get pregnant through IVF.
- What could go wrong
- This study only collected samples and did not test any treatment. It was terminated early, so the library may be incomplete and may not lead to any new discoveries.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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250 people
The number who actually took part.
- Started
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Nov 2022
- Finished
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Apr 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who consented to participate in the study, aged 18 to 43 consulting for infertility of at least 12 months, directed to IVF, of unexplained origin or presenting a low ovarian reserve before 35 years of age (AMH\<1.1ng and /or CFA\<7).
- Ages
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18 to 43 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Signed consent * Aged 18 to 43 * Infertility for at least 12 months * Oriented in IVF * Infertility of unexplained origin or presenting a low ovarian reserve before the age of 35 (AMH\<1.1ng and/or CFA\<7). Exclusion Criteria: * Minor patients or \> 43 years old * Patients under guardianship, curatorship (legal protection) * Refusal to participate * Patient unable to consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHRU de Brest
Brest, 29200, France
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Other studies related to the condition(s) this trial covers.
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