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Fasting for science: could a 60-Hour water fast boost cancer treatment?

NCT ID NCT07216989

Knowledge-focused Sponsor: University of Minnesota Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jul 15, 2026 · Updated 5 times

Summary

This study from the University of Minnesota is looking at what happens to your body when you fast for up to 60 hours, drinking only water. Researchers want to see if the changes in your blood can make cancer cells more sensitive to chemotherapy in lab tests. Fifteen healthy adults will wear continuous glucose monitors and give blood samples to track metabolic and cell marker changes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
prolonged fasting (water only for up to 60 hours)
What this could lead to
If successful, this could point toward new ways to use fasting to improve cancer treatment or manage insulin resistance.
What could go wrong
This is a very small, early observational study with only 15 people. It looks at lab effects, not actual patient outcomes, so real-world benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

14 people

The number who actually took part.

Started

Aug 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Self-reportedly healthy subjects

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Ages of 18-65 years old * Not pregnant * No comorbid conditions * BMI of 18.5-29.9. * Has a smartphone Exclusion Criteria: * Concern for active eating disorder per screening questionnaire * Self-reported eating disorder or history of eating disorder * History of hypoglycemia or contraindication for Prolonged Fasting * Weight \<120lbs * History of blood donation within the last 3 months.

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Conditions

The condition(s) this trial relates to.

Fasting Insulin Resistance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Fasting Insulin resistance

Contacts and locations

Locations

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.