Less propofol during brain surgery may lead to quicker, safer awakening
NCT ID NCT06844838
First seen Feb 18, 2026 · Last updated Jun 23, 2026 · Updated 17 times
Summary
This study is testing whether using lower doses of the anesthetic drug propofol during brain tumor surgery helps patients wake up more quickly and fully after the operation. Researchers will enroll 100 adults having elective brain surgery and monitor their recovery. The goal is to find the best balance between keeping patients asleep during surgery and ensuring a smooth, early awakening afterward.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fondazione IRCCS Istituto Neurologico Carlo Besta
RECRUITINGMilan, 20133, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
propofol and remifentanil (anesthetic drugs)
What this could lead to
If it works, this could lead to a standard way to give anesthesia that helps brain surgery patients wake up sooner and more clearly.
What could go wrong
This is a small, early-phase study (100 people) at one hospital. The results may not apply to all patients, and the approach might not improve outcomes or could have unknown risks.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.