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Mother-Daughter study tests if cleaning up your home can cut breast cancer risk

NCT ID NCT04265547

Knowledge-focused Sponsor: Columbia University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether mother-daughter pairs who change their household habits—like using chemical-free products and better cleaning—can lower their exposure to harmful chemicals and alter breast tissue composition. The goal was to see if these changes could reduce breast cancer risk. The trial involved 32 participants and measured chemical levels in urine and breast tissue using a special light-based machine.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
behavioral intervention (household cleaning and product changes)
What this could lead to
If successful, this could show that simple household changes reduce exposure to chemicals linked to breast cancer risk, pointing toward prevention strategies.
What could go wrong
This is a very small, early feasibility study with only 32 participants. It measures short-term changes in tissue and urine, not actual cancer outcomes, so results may not lead to clear health recommendations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

Jan 2020

Finished

Nov 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant of Columbia's Breast Cancer Research and the Environment (BCERP) Study that recruited from the Columbia Children's Center for Environmental Health (CCCEH) Mothers and Newborns cohort. * Mother did not smoke or use illicit drugs prior to or during pregnancy (referring to pregnancy for participating daughter). * Mother was 18-35 years at time of daughter's delivery. * Mother registered in the prenatal clinics by the 20th week of pregnancy. * Mother free of diabetes, hypertension and reported HIV infection. * Mother resided in northern Manhattan or the South Bronx neighborhoods of New York City for at least one year prior to pregnancy. * Mother self-identified as African-American or Dominican. * Only participants in the CCCEH birth cohort who answered in the affirmative to the question "I would like to be contacted about future studies" on the consent form of the Mothers and Newborns Study will be contacted to participate in this intervention. Exclusion Criteria: • None

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Conditions

The condition(s) this trial relates to.

breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer risk

Contacts and locations

Locations

  • Columbia University Mailman School of Public Health

    New York, New York, 10032, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.