Family history may raise risk of deadly aneurysm, swedish study suggests
NCT ID NCT07577128
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether brothers, sisters, and children of people who have had an abdominal aortic aneurysm are more likely to develop one themselves. Researchers will analyze health records from nearly one million people in Sweden. The goal is to better understand how family history affects risk, which could lead to better screening for those at highest risk.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify families who would benefit from early screening for abdominal aortic aneurysm.
- What could go wrong
- This is an observational study using existing data, so it cannot prove cause and effect. Results may not apply to other countries or populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 900,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Jan 2010
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Individuals with the diagnose AAA or the cause of death AAA in Sweden 2010-2024. The first-degree relatives have been identified through the Swedish multigeneration register and then a register based identifiaction if having AAA or not. All men and female over 45 years old are included.
- Ages
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45 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- Exclusion Criteria: * younger than 45 years.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Karolinska Institutet
Stockholm, Sweden
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Other studies related to the condition(s) this trial covers.
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