Karolinska University Hospital

This early-phase study tests a new radioactive drug, [177Lu]Lu-AKIR001, in 15 adults with advanced solid tumors (like thyroid, head and neck, cervical, vulvar, or lung cancer) that have a specific marker called CD44v6 and have stopped responding to standard treatments. The main g…

This study compares a new drug, trastuzumab deruxtecan (T-DXd), to standard treatment given before surgery for HER2-positive breast cancer that has not spread. About 370 adults will receive either T-DXd or standard care for three cycles, then further treatment is chosen based on …

This study compares robotic-assisted surgery to traditional open surgery for people with gallbladder cancer. The goal is to see if robotic surgery helps patients recover faster and leave the hospital sooner. About 94 adults who need gallbladder cancer surgery will take part, and …

This study examines whether starting continuous dialysis (CRRT) earlier in critically ill patients with severe kidney injury improves survival. Researchers will analyze data from over 50,000 patients from multiple ICUs in Sweden, comparing those who started dialysis early versus …

This study looks at why some people who have had a stem cell transplant continue to feel extremely tired and have trouble thinking clearly. Researchers will use brain scans and spinal fluid tests to see if inflammation in the brain is the cause. The goal is to better understand t…