Study links apathy to different fatigue types in seniors
NCT ID NCT04573712
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at how apathy (lack of motivation) influences different forms of fatigue in 57 older adults with mild cognitive disorders. Participants wore an activity tracker for a week and completed tests like a 6-minute walk and questionnaires. The goal was to compare fatigue levels between those with and without apathy, helping researchers understand these symptoms better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better understand the link between apathy and fatigue, potentially leading to improved care for people with mild cognitive disorders.
- What could go wrong
- This is a small, observational study with only 57 participants, so results may not apply to everyone. It does not test any treatment, so no direct health benefits are expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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57 people
The number who actually took part.
- Started
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Jan 2021
- Finished
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Dec 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men or women aged between 65 and 85 years old coming for consultation at the RMC and the Fragility Platform * DSM-5 diagnosis: minor neurocognitive disorders * Subject must read and write in French. * Subject must be registered in the national social security scheme. * Ability to sign free and informed consent. For the 'apathetic' group: \- Presence of apathy/emotional symptoms: at least 2 criteria according to the diagnostic criteria for apathy and a score higher than 8.5 in the MBI affective dimension. For the 'non-apathetic' group: \- Absence of apathy/emotional symptoms: no criteria according to the diagnostic criteria for apathy and a score of less than 8.5 in the MBI affective dimension. Exclusion Criteria: * Motor or sensory disabilities likely to interfere with the tests. * Presence of major psychiatric disorders (e.g., schizophrenia, major depressive episode, bipolar disorder) * Patient under guardianship, curatorship or under legal protection
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre Memoire Ressources et Recherche, CHU de Nice
Nice, 06000, France
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