New drug combo aims to halt metastatic breast cancer
NCT ID NCT03939897
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 25 times
Summary
This early-phase trial studies whether adding copanlisib to the standard drugs fulvestrant and abemaciclib can better control hormone receptor-positive, HER2-negative breast cancer that has spread. About 24 participants with stage IV cancer will receive either the three-drug combo or the standard two drugs alone. The goal is to find the safest dose and see if the new combination delays cancer growth.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Bellevue Hospital Center
New York, New York, 10016, United States
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Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York, 10016, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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Siteman Cancer Center at Christian Hospital
St Louis, Missouri, 63136, United States
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Siteman Cancer Center at Saint Peters Hospital
City of Saint Peters, Missouri, 63376, United States
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Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri, 63141, United States
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Siteman Cancer Center-South County
St Louis, Missouri, 63129, United States
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UC Irvine Health Cancer Center-Newport
Costa Mesa, California, 92627, United States
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UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, 92868, United States
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University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, 35233, United States
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University of Kentucky/Markey Cancer Center
Lexington, Kentucky, 40536, United States
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Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157, United States
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Wake Forest University at Clemmons
Clemmons, North Carolina, 27012, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Conditions
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