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Can village volunteers stop eye ulcers before they start?

NCT ID NCT01969786

Prevention Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time

Summary

This trial tests whether training female community health volunteers to diagnose and treat corneal abrasions can prevent corneal ulcers across many villages. Volunteers treat eye scratches with antifungal and antibiotic ointments three times a day for three days. Researchers compare ulcer rates in villages with the program to villages without it, using corneal photography to measure outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a prevention program where community volunteers treat eye scratches with antifungal and antibiotic ointments
What this could lead to
If the approach works, it could offer a low-cost way to prevent corneal ulcers in remote communities where eye specialists are scarce.
What could go wrong
Training volunteers to diagnose and treat eye injuries may not translate into fewer ulcers, and the ointments could cause allergic reactions or fail to stop infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

223,671 people

The number who actually took part.

Started

Feb 2014

Finished

Mar 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Presence of a corneal abrasion * Willingness to be treated with topical antibiotic and antifungal ointments 3 times a day for 3 days * Appropriate consent Exclusion Criteria: * Evidence of a corneal ulcer * Evidence of other acute eye disease requiring urgent care * Known allergy to study medications * Not willing to participate

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Conditions

The condition(s) this trial relates to.

corneal ulcer prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Corneal ulcer

Contacts and locations

Locations

  • Bharatpur Eye Hospital - Seva Foundation

    Bharatpur, Nepal

More trials for these conditions

Other studies related to the condition(s) this trial covers.