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Eye movements may reveal hidden brain fog after ICU

NCT ID NCT07676864

Knowledge-focused Sponsor: Shanghai Zhongshan Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

Some people have memory, attention, or thinking speed issues after leaving the ICU. This study explores whether a simple eye-tracking test can help identify these problems early. Adult patients who recently left the ICU will take a cognitive test and an eye-tracking test. The goal is to see if eye movement patterns can flag cognitive impairment, so doctors can offer follow-up care sooner.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If eye-tracking proves useful, it could give doctors a quick, non-invasive way to detect cognitive issues early after ICU discharge.
What could go wrong
This is a small observational study, not a treatment trial. Eye-tracking may not reliably identify cognitive problems, and results may not apply to all ICU survivors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 73 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of patients who have been successfully transferred from the intensive care unit (ICU) to a general ward after ICU treatment at Zhongshan Hospital, Fudan University. Eligible participants will have stayed in the ICU for at least 24 hours, be conscious, and be able to complete cognitive assessment and eye-tracking tests. Participants will undergo study assessments within 7 days after ICU discharge. No intervention will be assigned by the study.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Successfully transferred from the ICU to a general ward after ICU treatment. * ICU length of stay of at least 24 hours. * Conscious and able to cooperate with cognitive assessment and eye-tracking tests. * Willing to participate in the study and able to provide written informed consent. Exclusion Criteria: * Diagnosed with cognitive impairment before ICU admission, such as Alzheimer's disease, based on medical history or previous medical records. * Previous diagnosis of mental illness or intellectual developmental disorder. * Severe visual, hearing, or eye disease that prevents completion of cognitive assessment or eye-tracking tasks. * Severe neurological disease that may affect cognitive function, such as stroke, traumatic brain injury, or intracranial infection. * Unable to understand or complete the cognitive assessment or eye-tracking tasks due to severe fatigue, marked inattention, communication disorder, or other reasons as assessed by the research staff.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction postintensive care syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive impairment Post-intensive care syndrome (PICS)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Zhongshan hospital, Fudan university

    Shanghai, China

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