Can eye exercises tame migraines? new trial investigates
NCT ID NCT07254598
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding gentle eye muscle techniques to standard neck and jaw manual therapy can reduce pain and disability in people with migraine without aura. Eighty-four adults aged 18–65 will receive six physiotherapy sessions over eight weeks. Half will get the combined therapy; the other half will get manual therapy alone. Researchers will measure changes in pain, quality of life, and disability.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- myotensive extraocular muscle techniques and manual therapy
- What this could lead to
- If it works, this could offer a safe, non-drug way to reduce migraine pain and disability by combining eye muscle therapy with manual therapy.
- What could go wrong
- This is a small, early-stage trial with no blinding, so results may be influenced by placebo. The extra eye muscle techniques may not add benefit over manual therapy alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 84 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Being of legal age. * Having a medical diagnosis of migraine without aura established by a neurologist, according to the criteria of the ICHD-III * Having been diagnosed with migraine for at least one year and experiencing at least one attack per month. * Having been prescribed a specific pharmacological treatment by a specialist physician for at least 6 months. * Participants must attend all assessments with their habitual optical correction fully updated (glasses or contact lenses), ensuring that any refractive error is appropriately corrected. * Presenting symptoms in the oculomotor system, as detailed in the participant information sheet. Exclusion Criteria: * Pregnancy or breastfeeding. * Receiving any other type of physiotherapeutic treatment at the time of the intervention. * Presenting any of the following conditions: chronic respiratory, cardiovascular, and/or musculoskeletal diseases such as polyarthritis, rheumatic muscle inflammation, osteoporosis, or osteoarthritis; other types of headache, other neurological diseases, oncological processes, cognitive, emotional, or psychological disorders; previous surgical interventions or trauma in the cervical region; or diseases specific to the oculomotor system.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Universidad from Sevilla
Seville, Andalusia, 41009, Spain
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Other studies related to the condition(s) this trial covers.
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