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Eye fluid clues could unlock better treatment for wet AMD non-responders

NCT ID NCT07249216

First seen Jan 11, 2026 · Last updated Apr 30, 2026 · Updated 20 times

Summary

This study looks at fluid from inside the eyes of people with wet age-related macular degeneration (AMD) to understand why 20-40% do not respond well to standard anti-VEGF injections. Researchers will compare samples from good and poor responders to find other molecules driving the disease. The goal is to identify new targets for treatment or ways to predict who will benefit from current therapies. About 117 participants aged 50 and older will be followed for 24 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Singapore National Eye Centre/Singapore Eye Research Institute

    RECRUITING

    Singapore, Singapore

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.