New score could help Brain-Injured patients breathe on their own sooner
NCT ID NCT04080440
First seen Nov 01, 2025 · Last updated Jun 24, 2026 · Updated 37 times
Summary
This study tests a simple clinical score to help doctors decide when to remove breathing tubes from brain-injured patients who are still unconscious. The trial will include 660 patients across multiple ICUs. Half will use the score, and half will receive usual care. The goal is to see if the score reduces the need to put the breathing tube back in within 5 days.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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APHM
WITHDRAWNMarseille, France
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TERMINATEDBourg-en-Bresse, France
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TERMINATEDValence, France
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CHU
RECRUITINGAngers, France
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CHU
RECRUITINGBordeaux, France
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CHU
RECRUITINGBordeaux, France
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CHU
RECRUITINGCaen, France
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CHU
RECRUITINGClermont-Ferrand, France
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CHU
COMPLETEDGrenoble, France
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CHU
RECRUITINGLa Réunion, France
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CHU
RECRUITINGLille, France
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CHU
RECRUITINGMontpellier, France
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CHU
COMPLETEDNantes, France
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CHU
RECRUITINGNîmes, France
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CHU
RECRUITINGPoitiers, France
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CHU
RECRUITINGRennes, France
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CHU
COMPLETEDSaint-Etienne, France
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CHU
RECRUITINGToulouse, France
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Fondation Ophtalmologique Adolphe de Rothschild
RECRUITINGParis, France
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Hospices Civils de Lyon
RECRUITINGLyon, France
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Pasteur 2 Hospital - University Hospital
TERMINATEDNice, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Extubation readiness clinical score
What this could lead to
If successful, this score could become a standard tool to safely remove breathing tubes in brain-injured patients, reducing complications and time on a ventilator.
What could go wrong
This is a relatively early-stage trial testing a procedure, not a drug. The score may not work for all patients, and results may not apply outside this specific group.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.