Could a single friendly gut bacterium break the cycle of recurrent c. diff?
NCT ID NCT06306014
First seen Oct 31, 2025 · Last updated May 21, 2026 · Updated 32 times
Summary
This study tests EXL01, a capsule containing a single beneficial gut bacterium (Faecalibacterium prausnitzii), to see if it can prevent repeat Clostridioides difficile infections in people at high risk. About 56 adults who have had at least two or three C. diff episodes will take EXL01 or a placebo for 8 weeks. The goal is to see if restoring this missing bacterium can stop the infection from coming back.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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APHM La Timone Service de Maladies infectieuses
RECRUITINGMarseille, France
Contact Email: •••••@•••••
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CH Annecy Genevois Service de Maladies infectieuses
NOT_YET_RECRUITINGAnnecy, France
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CHU Grenoble Service Maladies infectieuses et tropicales
NOT_YET_RECRUITINGGrenoble, France
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Service d'Hépato-gastroentérologie Hôpital de la Croix Rousse
RECRUITINGLyon, 69004, France
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Service d'hépato-gastroentérologie - CHU Estaing
RECRUITINGClermont-Ferrand, 63003, France
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Service d'hépato-gastroentérologie - Hôpital Saint Antoine (APHP)
RECRUITINGParis, 75012, France
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Service d'infectiologie - Hôpital Nord / CHU Saint Etienne
NOT_YET_RECRUITINGSaint-Etienne, 42100, France
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Service de Maladies Infectieuses - CH de Valence
RECRUITINGValence, 26000, France
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Service de médecine interne - Pôle des maladies de l'appareil digestif - CHU de Toulouse
RECRUITINGToulouse, 31059, France
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Conditions
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