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Can exercise or brain games sharpen thinking in schizophrenia?

NCT ID NCT06572657

Disease control Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study tested whether aerobic exercise or computerized cognitive stimulation could improve thinking skills in 58 adults with schizophrenia. Participants were randomly assigned to one of the two activities. The goal was to see which approach better boosts memory, attention, and problem-solving. The results could help guide simple, non-drug ways to support mental function in schizophrenia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
aerobic exercise and computerized cognitive stimulation
What this could lead to
If successful, this could point toward a simple, drug-free way to help people with schizophrenia think more clearly and manage daily life better.
What could go wrong
This is a small, completed trial with only 58 participants, so results may not apply to everyone. It compares two non-drug approaches, so any benefit is likely modest and not a cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

58 people

The number who actually took part.

Started

Feb 2024

Finished

Sep 2024

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals diagnosed with schizophrenia by a physician according to DSM-V criteria Patients treated at TRSM Individuals diagnosed with schizophrenia between the ages of 20-60 Exclusion Criteria: * Those who did not give consent to participate in the study Patients with a diagnosis other than schizophrenia Pregnancy Patients with chronic metabolic diseases such as diabetes, heart problems and cancer

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Conditions

The condition(s) this trial relates to.

Motor Activity schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Computerized cognitive stimulation Exercise Schizophrenia

Contacts and locations

Locations

  • Kartal Dr Lütfi Kırdar Şehir Hastanesi

    Istanbul, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.