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Exercise program aims to beat fatigue in testicular cancer survivors

NCT ID NCT05588700

Symptom relief Sponsor: Centre Leon Berard Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a one-year supervised physical activity program can reduce long-term fatigue in men treated for metastatic testicular cancer. 236 participants will be randomly assigned to either the exercise program or standard recommendations. The main goal is to measure fatigue levels three years after starting chemotherapy.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
supervised physical activity program
What this could lead to
If it works, this could provide a proven way to reduce chronic fatigue and improve quality of life for testicular cancer survivors.
What could go wrong
This is a behavioral intervention, not a drug, so effects may be modest. The trial is still recruiting and results won't be available for several years.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 236 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Jan 2038

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men ≥18 years * With a metastatic germ cell tumor histologically confirmed (seminoma and non-seminoma) * Who have already undergone an orchidectomy (since the 16th december, this criteria was deleted). * Having a first line of chemotherapy planned with BEP, EP or VIP * Having a smartphone (i.e. to connect the activity tracker) * PS \< or = 2 * Whose ability to practice an adapted physical activity (APA) has been certified by a medical certificate issued by the referring oncologist or the investigating physician * Available and willing to participate in the study for the duration of the intervention and follow-up, * Able to understand, read and write French, * Affiliated with a social security scheme, * Having dated and signed an informed consent. Exclusion Criteria: * Presence of symptomatic bone and/or brain metastases * Central nervous system involvement with neurological deficits preventing walking * History or coexistence of another primary cancer (apart from in situ cancer of any location and/or basal cell skin cancer and/or basal cell skin cancer and/or a cancer in complete remission for more than 3 years), * Contraindication to physical activity (e.g. uncontrolled hypertension, uncontrolled heart disease) uncontrolled heart disease), * Unable to be followed for medical, social, family, geographical or psychological reasons, during the entire study period, * Deprived of liberty by judicial or administrative decision, or adults protected by law, * Concurrent participation in another study in PA.

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Conditions

The condition(s) this trial relates to.

Fatigue malignant testicular germ cell tumor testicular cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Metastatic testicular cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    12 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • AP-HP Tenon

    NOT_YET_RECRUITING

    Paris, 75020, France

  • CHU Jean Minjoz

    NOT_YET_RECRUITING

    Besançon, 25030, France

  • CHU Tours

    NOT_YET_RECRUITING

    Tours, 37000, France

  • Centre Antoine Lacassagne

    NOT_YET_RECRUITING

    Nice, 06189, France

  • Centre Eugène Marquis

    NOT_YET_RECRUITING

    Rennes, 35000, France

  • Centre François Baclesse

    NOT_YET_RECRUITING

    Caen, 14076, France

  • Centre Leon Berard

    RECRUITING

    Lyon, 69008, France

  • Centre Oscar Lambret

    NOT_YET_RECRUITING

    Lille, 59020, France

  • Institut Bergonié

    NOT_YET_RECRUITING

    Bordeaux, 33000, France

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, 94800, France

  • Institut de Cancérologie de Lorraine

    NOT_YET_RECRUITING

    Angers, 49000, France

  • Institut de Cancérologie de Lorraine

    RECRUITING

    Nancy, 54519, France

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