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Exercise before and during chemotherapy may boost treatment success

NCT ID NCT07502963

Symptom relief Sponsor: University of Vic - Central University of Catalonia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a supervised exercise program, started two weeks before chemotherapy and continued for 16 weeks during treatment, can help adults aged 35 to 65 with breast, lung, or colon cancer tolerate chemotherapy better. The goal is to see if participants can receive more than 85% of their planned chemotherapy dose and achieve a higher rate of complete tumor disappearance. Seventy participants will be randomly assigned to either the exercise program or usual care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
supervised exercise program
What this could lead to
If it works, this could show that a structured exercise program helps patients complete more of their chemotherapy and potentially improve treatment response.
What could go wrong
This is a small, early-stage trial with only 70 participants, so results may not apply to everyone. Exercise may not significantly improve chemotherapy tolerance or outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 70 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women and men aged 35 to 65 years * Diagnosed with stage II, III, or IV breast, lung, or colon cancer * Scheduled to start neoadjuvant chemotherapy * Able and willing to provide written informed consent Exclusion Criteria: * Musculoskeletal or neurological disorders that prevent proper execution of the exercises * Uncontrolled infections or symptoms * Comorbidities such as chronic obstructive pulmonary disease (COPD), respiratory failure, or recent cardiovascular events within the past 6 months * Body mass index (BMI) over 35 * Pregnant women * Difficulty understanding the purpose and procedures of the study

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm colon carcinoma colorectal cancer colorectal neoplasm lung cancer Motor Activity non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Colorectal cancer Lung cancer (non-small cell) Neoadjuvant chemotherapy tolerance Physical activity Strength and endurance

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Consorci Hospitalari de Vic

    Vic, Barcelona, 08500, Spain

  • Facultat de Ciències de la Salut i del Benestar de la Universitat de Vic (UVIC-UCC) Universitat de Vic- Universitat Central de Catalunya

    Vic, Barcelona, 08500, Spain

  • Hospital Universitari de la Santa Creu

    Vic, Barcelona, 08500, Spain

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