LUNG CANCER NON SMALL CELL

This study tests a new drug called MBRC-201 in people with advanced solid tumors (like prostate, breast, lung, colorectal, or pancreatic cancer) that have not responded to standard therapies. The drug is an antibody-drug conjugate, designed to deliver a cancer-killing agent direc…

This study tests an inhaled therapy called KB707 for people with advanced solid tumors that have spread to the lungs. KB707 is a modified virus designed to trigger the immune system to attack tumors. The trial involves 250 adults who have not responded to or cannot tolerate stand…

This study tests a combination of two drugs (IBI351 and cetuximab β) in people with advanced non-small cell lung cancer that has a specific genetic change called KRAS G12C. The goal is to see if the treatment shrinks tumors and controls the disease. About 48 adults who have not h…

This study tests a new drug called SKB571 in 295 adults with advanced non-small cell lung cancer. The goal is to see if it shrinks tumors and how safe it is. Participants receive the drug alone until their cancer worsens or side effects become too severe.

This study looks at whether giving veterans with lung cancer extra support can help them feel better day-to-day. About 194 veterans will take part, and researchers will track their quality of life using surveys. The goal is to see if simple added help can make a real difference.

This study looks at new methods to predict whether immunotherapy drugs (dostarlimab and pembrolizumab) will work in people whose non-small cell lung cancer has returned. Researchers will use blood samples, lab-grown tumor models, and special PET scans to see if these tools can fo…

This study looks at 450 people with central lung cancer who need a sleeve lobectomy (removing a tumor and part of the airway). It compares two minimally invasive techniques: robotic-assisted surgery (RATS) and video-assisted surgery (VATS). The goal is to see which approach leads…

This study follows 142 adults having lung cancer surgery to see if measuring nutrition and muscle loss can predict complications like infections or long hospital stays. Participants get blood tests, CT scans, and ultrasound before surgery. The goal is to create a risk score to he…

This study looks at whether doing intense exercise for two weeks before lung cancer surgery can change the tumor's surroundings and help the immune system fight better. Researchers will compare people who exercise with those who don't, and check tumor samples for changes. The goa…

This study watches 500 lung cancer patients who received immunotherapy before any other treatment. Researchers want to see if removing the whole lung or just part of it leads to better outcomes, and whether surgery is better than other treatments like radiation. The goal is to le…