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New hope for hard-to-treat lung cancer: drug duo targets KRAS mutation

NCT ID NCT07198841

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 29 times

Summary

This study tests a combination of two drugs (IBI351 and cetuximab β) in people with advanced non-small cell lung cancer that has a specific genetic change called KRAS G12C. The goal is to see if the treatment shrinks tumors and controls the disease. About 48 adults who have not had prior treatment for their advanced cancer will take part. The study is single-arm, meaning everyone gets the same treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Tumor Hospital of Guangxi Medical University

    NOT_YET_RECRUITING

    Nanning, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chinese PLA General Hospital

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University,

    RECRUITING

    Guangzhou, Guangdong, 510080, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First People's Hospital of Foshan

    RECRUITING

    Foshan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Fourth Hospital of Hebei Medical University

    NOT_YET_RECRUITING

    Shijiazhuang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Second Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The first affiliated hospital of nanchang university

    RECRUITING

    Nanchang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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