Can exercise and magnetic pulses ease schizophrenia symptoms in seniors?
NCT ID NCT07194460
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a device that sends magnetic pulses to nerves (peripheral magnetic stimulation) can reduce symptoms and improve daily function in older adults with schizophrenia. Forty participants aged 60 and older will be split into groups receiving either active or sham stimulation, or combining stimulation with exercise. The goal is to see if these approaches can help with thinking, mood, sleep, and physical abilities.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Peripheral Magnetic Stimulation (PMS) device and exercise
- What this could lead to
- If it works, this could offer a safe, drug-free way to improve symptoms, mobility, and quality of life for older adults with schizophrenia.
- What could go wrong
- This is a small, early-stage trial with only 40 participants, so results may not apply widely. The treatment is short-term (4 weeks), and benefits may be modest or not last.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
\# Eligibility Criteria * Inclusion Criteria: * Participants must be aged ≥60 years. * Diagnosis of schizophrenia based on the International Classification of Diseases - 10th Edition (ICD-10) or Diagnostic and Statistical Manual of Mental Disorders - 5th Edition (DSM-5). * Diagnosis must be made for ≥6 months, with clinical manifestations of schizophrenia (e.g., hallucinations, delusions, thought disorder, etc.). * No history of severe acute psychiatric episodes or hospitalizations within the last 3 months prior to enrollment. * Symptoms must be controllable, with no reliance on acute psychiatric intervention. * Participants must be able to understand the study's purpose and procedures and provide written informed consent. If the participant is unable to provide full informed consent (e.g., due to severe cognitive impairment), informed consent must be obtained from a legal guardian. * Exclusion Criteria: * Schizoaffective disorder or bipolar disorder with psychosis. * Elderly individuals with multiple chronic diseases but who still maintain good functional status and quality of life. * Presence of severe cardiovascular diseases, liver or kidney dysfunction, cerebrovascular diseases, or other physical conditions that may affect treatment. * Patients with contraindications to peripheral magnetic stimulation (PMS) treatment or EEG.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
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How to take part
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The official record
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