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Could taurine and Low-Oxygen recovery boost exercise benefits for obesity?

NCT ID NCT06579508

Disease control Sponsor: University of Sao Paulo Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether combining high-intensity interval training with recovery in low oxygen (hypoxia) and taurine supplements can improve body composition, metabolism, and mitochondrial function in women with obesity. Fifty women aged 25–45 with a BMI of 30–35 will exercise on a stationary bike and take either taurine or a placebo for 12 weeks. Researchers will measure changes in weight, fat mass, cholesterol, and muscle cell energy production.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
taurine
What this could lead to
If it works, this could point toward a more effective exercise-plus-supplement strategy for managing obesity and related metabolic issues.
What could go wrong
This is a small, early-phase study (50 women) with no blinding for the exercise component, so results may not apply broadly. Taurine and hypoxia effects are still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 45 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women * Age between 25 - 45 years old; * BMI between 30 - 35kg/m²; * Not be on a diet; * Not be on a physical activity program; * Not be menopaused. Exclusion Criteria: * Smokers; * Alcoholics; * Use thyroid medication; * Carry out nutritional monitoring or in treatment for weight loss; * Hypertension; * Metabolical syndrome; * Have any comorbidity associated to obesity; * Drugs use.

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Conditions

The condition(s) this trial relates to.

Motor Activity Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity

Contacts and locations

Locations

  • University of São Paulo, School of Physical Education and Sports of Ribeirão Preto

    Ribeirão Preto, São Paulo, 14049-900, Brazil

  • University of São Paulo, School of Physical Education and Sports of Ribeirão Preto.

    Ribeirão Preto, São Paulo, 14049-900, Brazil

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