Simple combo of exercise, fruit, and vitamins tested to reverse frailty in seniors
NCT ID NCT06225271
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a combination of exercise, fruit, and vitamin supplements can reduce frailty in older adults aged 65 to 80. About 934 participants with low physical activity and low fruit intake will be split into two groups: one receives the combined intervention three times a week for two months, plus group health education, while the other gets no intervention. The main goal is to see if handgrip strength improves after 12 months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- exercise, fruit, and vitamin supplementation
- What this could lead to
- If it works, this could provide a simple, non-drug way to help older adults stay stronger and more independent.
- What could go wrong
- This is a relatively small, early-stage trial with a short intervention period. The results may not apply to all older adults, and the benefits might be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 934 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2024
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Permanent resident population aged 65\~80 years; 2. Able to walk independently indoors and outdoors; 3. Physical activity less than 1400 metabolic equivalent task (MET)-min/week and fruit intake less than 50 g/day; 4. Have not taken vitamin B and vitamin C supplementation in the past 3 months. Exclusion Criteria: 1. Presence of a history of fracture; 2. Patients with severe impairment of renal or hepatic fuction. Severe hepatic impairment is defined as serum alanine aminotransferase and aspartate aminotransferase levels above 100 U/L, while severe renal impairment is defined as estimated glomerular filtration rate (eGFR) \< 45 mL/min, calculated according to the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Suzhou Center for Disease Control and Prevention
Suzhou, Jiangsu, China
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Other studies related to the condition(s) this trial covers.
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