Can one weekly workout beat fatty liver? new study tests the ideal exercise frequency
NCT ID NCT05741957
First seen May 02, 2026 · Last updated Jun 19, 2026 · Updated 7 times
Summary
This study looks at whether exercising once a week or three times a week is better at reducing liver fat in adults who are centrally obese and have non-alcoholic fatty liver disease (NAFLD). Three hundred Chinese adults aged 18-69 will be assigned to either a once-weekly or thrice-weekly supervised treadmill program for 4 months. The goal is to find the most practical exercise frequency that still meets health recommendations and helps improve liver health.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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LKS Faculty of Medicine
Hong Kong, Hong Kong
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
supervised treadmill exercise program
What this could lead to
If it works, this could show that even once-a-week exercise can meaningfully reduce liver fat, offering a practical option for busy people with NAFLD.
What could go wrong
This is a behavioral study with no blinding, so results may be influenced by participants' expectations. The effect may be modest and not apply to all NAFLD patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.