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Can hand exercises boost brain power in mild cognitive impairment?

NCT ID NCT06935812

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether different hand exercises—using both hands, just fingers, or virtual reality games—can improve thinking and memory in people with mild cognitive impairment. 106 adults aged 50-75 will do 40-minute sessions three times a week for 8 weeks. Researchers will measure changes in cognitive tests like the Montreal Cognitive Assessment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
exercise (bimanual, finger, and virtual reality)
What this could lead to
If successful, this could point toward simple, non-drug exercises that help maintain or improve memory and thinking skills in people with mild cognitive impairment.
What could go wrong
This is a small, early-stage study (106 people) comparing different types of exercise. Results may not apply to everyone, and the improvements might be modest or temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 106 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants who are between 50-75 years of age * Individuals diagnosed with MCI by a geriatrician according to DSM-5 criteria, * Who has the Montreal Cognitive Assessment score between 13-26, * Who has the Quick Mild Cognitive Impairment screen score between 48-67, * Who has Instrumental Activities of Daily Living Scale score ≥6/8, * Who says yes to "Do you have a memory problem?" question, * Who can walk independently without using any walking aids Exclusion Criteria: * Participants who have any musculoskeletal disorders that may cause balance and gait disorders, * Who have central or peripheral neurological diseases (eg. stroke, Parkinson's disease or polyneuropathies), * Who are using psychiatric drugs that may affect psychiatric disease and/or cognitive performance (Using nonsteroidal anti-inflammatory drugs more than three times a week, which may affect cognitive functions, using gingko biloba and antioxidant supplements (for example, coenzyme Q10 and alpha-lipoic acid)), * Who has daltonism and * Who attends any exercise program last 6 months will not be included in this study.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Eastern Mediterranean University

    RECRUITING

    Famagusta, Eyalet/Yerleşke, 99450, Cyprus

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