Can hand exercises boost brain power in mild cognitive impairment?
NCT ID NCT06935812
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether different hand exercises—using both hands, just fingers, or virtual reality games—can improve thinking and memory in people with mild cognitive impairment. 106 adults aged 50-75 will do 40-minute sessions three times a week for 8 weeks. Researchers will measure changes in cognitive tests like the Montreal Cognitive Assessment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- exercise (bimanual, finger, and virtual reality)
- What this could lead to
- If successful, this could point toward simple, non-drug exercises that help maintain or improve memory and thinking skills in people with mild cognitive impairment.
- What could go wrong
- This is a small, early-stage study (106 people) comparing different types of exercise. Results may not apply to everyone, and the improvements might be modest or temporary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 106 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Apr 2025
- Expected to finish
-
Sep 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
50 to 75 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants who are between 50-75 years of age * Individuals diagnosed with MCI by a geriatrician according to DSM-5 criteria, * Who has the Montreal Cognitive Assessment score between 13-26, * Who has the Quick Mild Cognitive Impairment screen score between 48-67, * Who has Instrumental Activities of Daily Living Scale score ≥6/8, * Who says yes to "Do you have a memory problem?" question, * Who can walk independently without using any walking aids Exclusion Criteria: * Participants who have any musculoskeletal disorders that may cause balance and gait disorders, * Who have central or peripheral neurological diseases (eg. stroke, Parkinson's disease or polyneuropathies), * Who are using psychiatric drugs that may affect psychiatric disease and/or cognitive performance (Using nonsteroidal anti-inflammatory drugs more than three times a week, which may affect cognitive functions, using gingko biloba and antioxidant supplements (for example, coenzyme Q10 and alpha-lipoic acid)), * Who has daltonism and * Who attends any exercise program last 6 months will not be included in this study.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Mild cognitive impairment are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Eastern Mediterranean University
RECRUITINGFamagusta, Eyalet/Yerleşke, 99450, Cyprus
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Walking memory tests may reveal early Parkinson's clues
- Can tango rewire the brain? dance program tested for Parkinson's and dementia
- Can tiny bursts of baduanjin exercise sharpen a fading memory?
- Can pool workouts plus brain games sharpen memory in aging veterans?
- Can home exercise keep older adults with cognitive frailty on their feet?
- A new roadmap to predict Alzheimer's before memory fails