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Exercise program aims to restore energy flexibility in breast cancer survivors

NCT ID NCT07405385

Symptom relief Sponsor: University of Castilla-La Mancha Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a 16-week supervised exercise program can help breast cancer survivors improve their body's ability to switch between burning carbs and fats for energy. Researchers will enroll 44 women aged 18-70 who completed chemotherapy within the last 6 months and are on hormone therapy. Participants will do twice-weekly aerobic and strength training sessions, and their metabolic flexibility and fitness will be measured before, after, and at a 3-month follow-up.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 44 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged between 18 and 70 years. * Confirmed diagnosis of breast cancer in stages I to III. * Received neo-adjuvant or adjuvant chemotherapy and completed the chemotherapy treatment within the 6 months prior to study enrolment. * Residency within a distance of less than 40 km from the Hospital Universitario de Toledo. Exclusion Criteria: * Diagnosis of stage IV breast cancer. * Undergone major surgery within the 4 months prior to enrolment or scheduled for breast reconstruction surgery during the study period. * Diagnosis of diabetes mellitus with poor glycaemic control, defined as an HbA1c value greater than or equal to 8.5%. * Presence of an acute infectious disease. * Absolute or relative medical contraindications for physical exercise or maximal exercise stress testing, according to the American College of Sports Medicine (ACSM) guidelines. * Serious cardiac or cardiovascular disease, including a history of myocardial infarction, heart failure, or known cardiomyopathy. * Regular consumption of beta-blockers or any medication that alters the functioning of the nervous system. * Currently active, defined as engaging in more than 150 minutes per week of structured physical exercise during the 6 months prior to enrolment.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Cancer Cardiotoxicity Metabolic flexibility Neoplasm

How to take part

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  1. The places running it

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  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • University of Castilla-La Mancha (PAFS Research Group)

    Toledo, Toledo, 45071, Spain

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