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Which workout is best for heart failure? new study aims to find out

NCT ID NCT07519473

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two supervised exercise programs—neuromuscular training (focusing on balance and coordination) and resistance training (using weights and bands)—in 40 adults with chronic heart failure. Over 10 weeks, researchers will measure how far participants can walk, their heart and lung fitness, and lower body strength. The goal is to identify the more effective rehabilitation approach to improve daily function and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
exercise training (neuromuscular or resistance)
What this could lead to
If successful, this could show which type of exercise is better for helping heart failure patients walk farther, breathe easier, and feel stronger in daily life.
What could go wrong
This is a small, early-stage trial with only 40 people, so results may not apply to all heart failure patients. Exercise programs also require ongoing commitment to maintain benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male and female patients aged 40-60 years * Diagnosed with chronic heart failure ≥ 1 year * Heart failure with reduced ejection fraction (HFrEF), EF ≤ 40% * NYHA Class II-III * Low to moderate exercise risk (based on Chester Step Test) * On stable pharmacological treatment for ≥ 6 weeks * Able to understand and follow exercise instructions Exclusion Criteria: * Absolute contraindications to exercise (e.g., recent MI, unstable angina, uncontrolled arrhythmias, severe aortic stenosis, decompensated HF) * Abnormal CPET findings (severe arrhythmias, ischemia, ST depression) * Abnormal blood pressure response during exercise * Exercise-induced angina or thoracic pain * Musculoskeletal, neurological, or cognitive impairments limiting exercise participation

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • community based Cardiac Rehab Unit, Cardiac Centers, and Tertiary Care Hospitals

    Lahore, Punjab Province, 40100, Pakistan

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