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Exercise may be the key to pain relief after menopause

NCT ID NCT07407699

Symptom relief Sponsor: São Paulo State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a 12-month exercise program can reduce chronic pain in postmenopausal women. The program includes walking or cycling, strength training, and gentle yoga. Researchers think that improving insulin resistance and reducing inflammation might be how exercise helps. Fifty women who are not on hormone therapy and do not exercise regularly will take part.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
combined exercise program (aerobic, resistance, and mind-body exercises)
What this could lead to
If it works, this could point toward a non-drug treatment for chronic pain in postmenopausal women, possibly by improving how the body handles insulin.
What could go wrong
This is a small, early-stage study with only 50 participants, so results may not apply to everyone. Exercise programs also require long-term commitment, and benefits may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Postmenopausal women, defined as between 12 months and 5 years since the last menstrual period. * Not using hormone replacement therapy. * Not engaged in regular physical exercise (defined as more than once per week in the last months). * With or without insulin resistance. Exclusion Criteria: * Diagnosis of neurological diseases (e.g., Parkinson's disease, multiple sclerosis, or stroke sequelae). * Severe psychiatric disorders. * Inflammatory autoimmune diseases (e.g., rheumatoid arthritis or systemic lupus erythematosus). * Active neoplasms. * Use of systemic corticosteroids or immunosuppressive drugs within the last three months. * Severe decompensated cardiovascular disease. * Any medical condition that contraindicates participation in physical exercise.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome Insulin Resistance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic pain Insulin resistance Postmenopausal

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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