Exercise program shows promise for controlling blood pressure in hypertensive patients
NCT ID NCT03923907
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a special exercise program could help people with high blood pressure, especially those whose blood pressure doesn't drop enough during sleep (a condition linked to higher heart risks). 198 Chinese adults who did little exercise were split into two groups: one received the exercise program plus usual care, the other just usual care. The goal was to see if exercise could improve blood pressure patterns and overall control.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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198 people
The number who actually took part.
- Started
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Sep 2021
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * SBP non-dippers * self-reported exercise intensity and duration less than the World Health Organization recommendation, which is exercise of moderate intensity less than 150minutes/week OR exercise of vigorous intensity of less than 75 minutes/week * Used any mobile apps on their phone (because the intervention involve use of apps to monitor and remind regular exercise) Exclusion Criteria * Patients with diagnosed chronic obstructive lung disease and recent stroke (within last 12 months) because other evidence-proven and well-structured programmes are implemented for these patients in the hospital authority in Hong Kong * Occupational drivers - because they need to hold their arm still during ABPM and this may be hazardous for drivers * night-time workers * diagnosed Obstructive Sleep Apnea * Patients on anti-coagulants - because ABPM may induce bruises * Patients on 3 or more medications for hypertension (on maximum tolerable doses) - these patients may have secondary HT and represent a different spectrum of organic diseases * Patients with SBP \>180mmHg or DBP \>110mmHg - drug titration is not allowed during the 12-week program and these patients need early drug treatment * Patient with DM - these patients will be arranged to have another EIM program especially designed for their DM. * Patients with active spinal cord compression or spinal radiculopathy because they may not be suitable to join some exercise * patients with atrial fibrillation are excluded because these patients have increased BP variability and may have different dipping behaviour * patients with metallic implants or pacemakers are excluded as they are not suitable for MRI * To maximize safety of patients, patients who are relatively contraindicated according to AHA will also be excluded * acute myocardial infarction in last 6 months * ongoing angina * uncontrolled cardiac arrhythmia * acute diseases including known active endocarditis/acute pulmonary embolism, pulmonary infarction, deep vein thrombosis, acute aortic dissection, acute myocarditis * known aortic stenosis * known heart failure * known obstructive left main coronary artery stenosis * uncontrolled ventricular rates * complete heart block * known hypertrophic obstructive cardiomyopathy * mental impairment that limit co-operation * resting blood pressure with systolic blood pressure \>180mmHg or diastolic blood pressure \>110mmHg * known anemia with hemoglobin level less than 11gm/dL * known uncorrected electrolyte imbalance, and * known uncontrolled hyperthyroidism.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Lek Yuen Clinic
Hong Kong, Hong Kong
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Other studies related to the condition(s) this trial covers.
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