Pedaling while dialyzing: new study tests exercise to fight muscle wasting in kidney patients
NCT ID NCT07151742
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether a 12-week exercise program done during dialysis can improve muscle oxygen levels and dialysis quality in kidney patients who also have muscle loss (sarcopenia). About 40 patients will either exercise on a bike and do resistance moves during their first two hours of dialysis, or continue usual care. Researchers will measure muscle oxygen, dialysis effectiveness, strength, and quality of life before and after the program.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- intradialytic combined exercise program (aerobic cycling and resistance training)
- What this could lead to
- If it works, this could offer a simple, drug-free way to improve muscle health and dialysis effectiveness for kidney patients.
- What could go wrong
- This is a small, early-stage trial with only 40 participants. The exercise program may be too demanding for some patients, and results may not apply to all kidney patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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Dec 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Age between 18 and 65 years Diagnosed with stage 5 chronic kidney disease (end-stage renal disease) according to GFR, undergoing maintenance hemodialysis for at least 1 year Diagnosed with sarcopenia based on EWGSOP2 (2018) criteria Able to read and write Cooperative and able to follow instructions Voluntary participation with written informed consent Exclusion Criteria: Presence of orthopedic or neurological disorders affecting mobility or exercise capacity Uncontrolled diabetes mellitus or uncontrolled hypertension Untreated intradialytic hypotension Heart failure Unstable angina \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Kadıköy Ata Dialysis Center
Istanbul, Kadikoy, 34720, Turkey (Türkiye)
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