Can exercise lower diabetes risk in breast cancer survivors?
NCT ID NCT06830486
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at how physical activity, fitness, and sitting time relate to insulin resistance (a diabetes risk factor) in 40 breast cancer survivors taking hormone therapy. Participants wore activity monitors and underwent tests for fitness, body composition, and insulin resistance. The goal is to understand how lifestyle factors might influence diabetes risk in this group.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could help identify ways to reduce diabetes risk in breast cancer survivors through exercise and lifestyle changes.
- What could go wrong
- This is an observational study with only 40 participants, so results may not apply to all survivors. It does not test a treatment, so direct benefits are limited.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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40 people
The number who actually took part.
- Started
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Feb 2022
- Finished
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Oct 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Breast cancer survivors prescribed endocrine therapy for at least one year
- Ages
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18 to 80 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female * diagnosed with breast cancer * age 18-80 years * Completed surgery, chemo- and/or radiation therapy * Prescribed aromatase inhibitor or SERM for at least one year from the time of screening Exclusion Criteria: * Age \< 18 or \> 80 * Type 1 diabetes * Type 2 diabetes * Prescribed anti-hyperglycemic medication, insulin, or sulfonylurea. * Pregnant, breastfeeding or planning to become pregnant in next 2 months * Have absolute contraindications to exercise testing which are: 1. Unstable angina 2. Recent myocardial infarction, cardiac surgery, or vascular surgery (\<3 months) 3. Uncontrolled high blood pressure 4. Heart failure 5. Peripheral artery disease (based on report of symptomatic claudication) 6. Hepatic or renal disease 7. Severe arthritis or mobility impairment that would interfere with exercise testing * Suspected cognitive impairment that would prevent understanding or comprehension of study procedures.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Of Colorado Anschutz Medical Campus
Aurora, Colorado, 80045, United States
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