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Can exercise lower diabetes risk in breast cancer survivors?

NCT ID NCT06830486

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at how physical activity, fitness, and sitting time relate to insulin resistance (a diabetes risk factor) in 40 breast cancer survivors taking hormone therapy. Participants wore activity monitors and underwent tests for fitness, body composition, and insulin resistance. The goal is to understand how lifestyle factors might influence diabetes risk in this group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help identify ways to reduce diabetes risk in breast cancer survivors through exercise and lifestyle changes.
What could go wrong
This is an observational study with only 40 participants, so results may not apply to all survivors. It does not test a treatment, so direct benefits are limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Feb 2022

Finished

Oct 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Breast cancer survivors prescribed endocrine therapy for at least one year

Ages

18 to 80 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female * diagnosed with breast cancer * age 18-80 years * Completed surgery, chemo- and/or radiation therapy * Prescribed aromatase inhibitor or SERM for at least one year from the time of screening Exclusion Criteria: * Age \< 18 or \> 80 * Type 1 diabetes * Type 2 diabetes * Prescribed anti-hyperglycemic medication, insulin, or sulfonylurea. * Pregnant, breastfeeding or planning to become pregnant in next 2 months * Have absolute contraindications to exercise testing which are: 1. Unstable angina 2. Recent myocardial infarction, cardiac surgery, or vascular surgery (\<3 months) 3. Uncontrolled high blood pressure 4. Heart failure 5. Peripheral artery disease (based on report of symptomatic claudication) 6. Hepatic or renal disease 7. Severe arthritis or mobility impairment that would interfere with exercise testing * Suspected cognitive impairment that would prevent understanding or comprehension of study procedures.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Insulin Resistance Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Of Colorado Anschutz Medical Campus

    Aurora, Colorado, 80045, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.