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Muscle loss in aging: can diet and exercise turn back the clock?

NCT ID NCT07761091

Disease control Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial tests whether a 24-week program of physical activity, alone or combined with nutritional support, can improve muscle mass, strength, and walking speed in older adults with sarcopenia—a condition marked by age-related muscle loss. Participants aged 60-70 in Vietnam are randomly assigned to one of three groups: health education only, physical activity, or physical activity plus nutrition. The study measures changes in muscle mass and strength over six months to see if the combined approach offers extra benefits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A 24-week physical activity program and a combined physical activity plus nutritional support intervention, compared with health education alone.
What this could lead to
If effective, this approach could offer a practical, non-drug strategy to slow or reverse muscle loss and improve strength and mobility in older adults with sarcopenia.
What could go wrong
The trial is relatively small (90 participants) and the results may not apply to all older adults. The benefits might be modest or not sustained after the program ends.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

Jan 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 60-70 years and residing in Can Gio District, Ho Chi Minh City, Vietnam. * Listed in the local Older Persons Association registry. * Diagnosed with sarcopenia according to the Asian Working Group for Sarcopenia (AWGS) 2019 criteria. * Able to walk independently. * Willing to participate in the study and provide written informed consent. Exclusion Criteria: * Recent or current participation in another clinical trial or dietary or physical activity intervention program. * Current treatment for cancer or other malignancies. * Chronic kidney disease requiring maintenance dialysis. * Poorly controlled or unstable chronic obstructive pulmonary disease. * Current musculoskeletal disease, recent injury, or recent surgery that limits physical activity. * Current use of medications that may affect study outcomes, including weight-loss medications, corticosteroids, or thyroid hormones. * Contraindication to the oral nutritional supplement (ONS) used in the study.

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Conditions

The condition(s) this trial relates to.

Motor Activity Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sarcopenia

Contacts and locations

Locations

  • Can Gio

    Ho Chi Minh City, Ho Chi Minh, 70000, Vietnam

More trials for these conditions

Other studies related to the condition(s) this trial covers.