Could interval training strengthen hearts after aortic repair?
NCT ID NCT07771023
First seen Aug 18, 2026 · Last updated Aug 26, 2026 · Updated 3 times
Summary
This study tests whether high-intensity interval training (HIIT) can improve cardiovascular health in adults who had surgery to repair coarctation of the aorta, a narrowing of the main artery. Participants are randomly assigned to do HIIT at home, HIIT in a supervised clinic, or receive usual care. The trial measures changes in exercise capacity, blood pressure response, quality of life, and other heart health indicators to see if this type of exercise offers benefits.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- High-intensity interval training (HIIT) exercise programme
- What this could lead to
- If effective, HIIT could become a recommended way to boost fitness and heart health in people who had coarctation repair, potentially improving long-term outcomes.
- What could go wrong
- This is a relatively small trial, and results may not apply to everyone. Exercise carries some risk, especially for those with heart conditions, so supervision and screening are important.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 45 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * surgically repaired coarctation of the aorta, * age at least 18 years, and * signed informed consent form. Exclusion Criteria: * residual aortic stenosis (gradient across the narrowing \>20 mmHg), * presence of ascending aortic aneurysm, * recent major cardiovascular event or other event requiring hospitalization (event less than 2 months before inclusion), * unstable rhythm disturbances, * unstable or low-threshold angina pectoris, * NYHA class III or IV heart failure, and * pregnancy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Medical Centre Ljubljana
Ljubljana, 1000, Slovenia
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University Medical Centre Maribor
Maribor, 2000, Slovenia
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