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Can exercise boost brain health in cannabis users? new study investigates
NCT ID NCT06081218
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how a single session of exercise changes blood markers related to brain health in people who use cannabis regularly compared to those who don't. Researchers will measure endocannabinoids and other substances in the blood, along with cognitive tests. The goal is to understand if exercise affects the brain differently in chronic cannabis users.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2024
- Expected to finish
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Dec 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 35 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Cannabis consumer group: * Cannabis consumption \> 100 times in lifetime, last exposure \< 7 days, and recent exposure \> 10 times in the month. * Positive toxicological urine test for ∆-9-THC. * Having a cannabis use disorder according to the CAST. Healthy group: * Negative urine toxicological test for cannabis. * No regular cannabis use for more than 6 months once in a lifetime. * No cannabis consumption in the 6 months preceding the study. Exclusion Criteria: For all subjects : * Disorders of use of other substances (alcohol, cocaine, opioid, or synthetic drugs). * Alcohol consumption greater than 30g per day (averaged over one week) and/or alcohol abuse the week preceding the visit. * Under medical treatment. * Presence of diagnosed neurological disorders. * Diagnosis of a psychotic picture entering axis I, DSM-5. * Chronic progressive disease or in remission. * Body mass index \> 30 kg/m2 (i.e. presence of obesity).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU Lille
RECRUITINGLille, 59000, France
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Other studies related to the condition(s) this trial covers.
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