Lung blood tests may guide smarter treatment for pulmonary hypertension
NCT ID NCT01961232
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether adding special blood tests (biomarkers) to the usual heart-lung exam can help doctors pick the right therapy for people with pulmonary hypertension. About 100 adults undergoing a routine heart catheterization will have extra blood samples taken from their lungs. The goal is to see if these markers lead to better treatment choices and improved outcomes.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2013
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Pulmonary Vascular Clinic
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years old * Undergoing RHC for PH evaluation Exclusion Criteria: * Anemia defined as Hgb \< 10 g/dL and HCT \< 30 * Pregnancy at the time of RHC (as assessed by urine or serum pregnancy test on the day of the procedure) * Left ventricular ejection fraction ≤ 40% * Atrial fibrillation at the time of RHC (as defined by telemetry monitoring or EKG on the day of the procedure) * IPF, CTEPH, COPD/OSA as the dominant etiology of PH * Patient is currently taking PH medication or long-acting nitrates at the time of their RHC.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
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Other studies related to the condition(s) this trial covers.
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