Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Less oxygen may save more lives after cardiac arrest, study hints

NCT ID NCT03138005

Disease control Sponsor: Monash University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving less oxygen (aiming for 90-94% oxygen in the blood) right after a cardiac arrest outside the hospital helps more people survive to leave the hospital. It included 428 unconscious adults who had been revived and were on a breathing tube. The trial was stopped early, but results may guide future oxygen use in emergency care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

428 people

The number who actually took part.

Started

Dec 2017

Finished

Aug 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (age 18 years or older) * Out-of-hospital cardiac arrest of presumed cardiac cause * All cardiac arrest rhythms * Unconscious (Glasgow Coma Scale \<9) * Return of spontaneous circulation * Pulse oximeter measures oxygen saturation at ≥95% with oxygen flow set at \>10L/min or FiO2 at 100% * Patient has an endotracheal tube (ETT) or supraglottic airway (SGA) (e.g. laryngeal mask airway -LMA) and is spontaneously breathing or ventilated * Transport is planned to a participating hospital Exclusion Criteria: * Female who is known or suspected to be pregnant * Dependent on others for activities of daily living (i.e. facilitated care or nursing home residents) * "Not for Resuscitation" order or Advanced Care Directives in place * Pre-existing oxygen therapy (i.e. for COPD) * Cardiac arrest due to drowning, trauma or hanging

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Out-of-hospital cardiac arrest are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

cardiac arrest Out-of-Hospital Cardiac Arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Out-of-hospital cardiac arrest

Contacts and locations

Locations

  • Alfred Hospital

    Melbourne, Victoria, 3004, Australia

  • Ambulance Victoria

    Melbourne, Victoria, 3130, Australia

  • Austin Hospital

    Melbourne, Victoria, 3084, Australia

  • Barwon Health: Geelong

    Melbourne, Victoria, 3220, Australia

  • Box Hill Hospital

    Melbourne, Victoria, 3128, Australia

  • Eastern Health: Maroondah Hospital

    Melbourne, Victoria, 3135, Australia

  • Fiona Stanley Hospital

    Perth, Western Australia, 6150, Australia

  • Lyell McEwin Hospital

    Adelaide, South Australia, 5112, Australia

  • Monash Medical Centre

    Melbourne, Victoria, 3168, Australia

  • Northern Health: The Northern Hospital

    Melbourne, Victoria, 3076, Australia

  • Peninusla Health: Frankston Hospital

    Melbourne, Victoria, 3199, Australia

  • Royal Adelaide Hospital

    Adelaide, South Australia, 5000, Australia

  • Royal Perth Hospital

    Perth, Western Australia, 6000, Australia

  • SA Ambulance Service

    Adelaide, South Australia, 5063, Australia

  • Sir Charles Gairdner Hospital

    Perth, Western Australia, 6009, Australia

  • St John Ambulance Western Australia

    Perth, Western Australia, 6984, Australia

  • St Vincents Hospital

    Melbourne, Victoria, 3065, Australia

  • The Queen Elizabeth Hospital

    Adelaide, South Australia, 5011, Australia

  • The Royal Melbourne Hospital

    Melbourne, Victoria, 3050, Australia

  • Western Health: Footscray Hospital

    Melbourne, Victoria, 3011, Australia

  • Western Health: Sunshine Hospital

    Melbourne, Victoria, 3021, Australia

More trials for these conditions

Other studies related to the condition(s) this trial covers.