New drug EVOLVE104 targets tough cancers in early trial
NCT ID NCT07217171
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 33 times
Summary
This early-phase study tests a new drug, EVOLVE104, in people with advanced bladder cancer or several types of squamous cell cancers (lung, esophagus, skin, and others) that have worsened after standard treatments. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. About 160 participants will receive the drug and be closely monitored for side effects and cancer response.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Email: •••••@•••••
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
Contact Email: •••••@•••••
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SCRI
RECRUITINGNashville, Tennessee, 37203, United States
Contact Email: •••••@•••••
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START Midwest
RECRUITINGGrand Rapids, Michigan, 49546, United States
Contact Email: •••••@•••••
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The Winship Cancer Institute Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
Contact Email: •••••@•••••
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Thomas Jefferson University, Sidney Kimmel Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Email: •••••@•••••
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USC/Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
Contact Email: •••••@•••••
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Virginia Cancer Specialists
RECRUITINGFairfax, Virginia, 22031, United States
Contact Email: •••••@•••••
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Yale University Cancer Center
RECRUITINGNew Haven, Connecticut, 06511, United States
Contact Email: •••••@•••••
Conditions
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