New hope for tough cancers? EVOLVE104 trial opens for advanced bladder and squamous cell cancers
NCT ID NCT07217171
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 34 times
Summary
This early-stage trial tests a new drug, EVOLVE104, in about 160 people with advanced bladder cancer or several types of squamous cell cancer (lung, esophagus, skin, and others). Participants must have already tried standard treatments or be unable to take them. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Email: •••••@•••••
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
Contact Email: •••••@•••••
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SCRI
RECRUITINGNashville, Tennessee, 37203, United States
Contact Email: •••••@•••••
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START Midwest
RECRUITINGGrand Rapids, Michigan, 49546, United States
Contact Email: •••••@•••••
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The Winship Cancer Institute Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
Contact Email: •••••@•••••
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Thomas Jefferson University, Sidney Kimmel Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Email: •••••@•••••
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USC/Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
Contact Email: •••••@•••••
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Virginia Cancer Specialists
RECRUITINGFairfax, Virginia, 22031, United States
Contact Email: •••••@•••••
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Yale University Cancer Center
RECRUITINGNew Haven, Connecticut, 06511, United States
Contact Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.