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New procedure zaps nerve pain for pancreatic cancer patients

NCT ID NCT05535894

First seen May 03, 2026 · Last updated Jun 23, 2026 · Updated 9 times

Summary

This study tested a procedure called endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) to relieve pain in 19 people with advanced pancreatic cancer that could not be removed by surgery. The procedure uses heat to target nerves that cause pain. Researchers measured pain levels, quality of life, and how much pain medication patients needed. The goal was to see if this approach could improve comfort and reduce reliance on strong painkillers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Shailendra Singh

    Morgantown, West Virginia, 26508, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiofrequency ablation procedure

What this could lead to

If it works, this could offer a new way to manage severe pain and reduce the need for strong painkillers in people with advanced pancreatic cancer.

What could go wrong

This was a small, early study with only 19 participants, so results may not apply to everyone. The procedure carries risks like bleeding or infection, and pain relief may be temporary.

Conditions

The condition(s) this trial relates to.

pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.