Shock wave or ozone: which works better for stubborn tennis elbow?
NCT ID NCT07427368
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two treatments for people with long-lasting tennis elbow (lateral epicondylitis) that hasn't improved with standard care. Fifty adults will receive either shock wave therapy or an ozone injection once a week for three weeks. Researchers will measure pain, elbow function, grip strength, and tendon changes before treatment, right after, and one month later to see which approach works better.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2025
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age: Male or female patients between 18 and 65 years of age. * Clinical Diagnosis: Patients diagnosed with lateral epicondylitis, defined by pain in the lateral epicondyle region for more than 3 months, increased pain on palpation of the lateral epicondyle, and positive provocation tests (Cozen's, Maudsley's, or Mills' tests). * Symptom Duration: Presence of symptoms for more than 3 months (resistant cases). * Treatment Failure: Lack of response to first-line conservative treatments (e.g., analgesics, exercise, rest, splinting). * Radiographic Confirmation: No other pathology detected on direct radiographs of the elbow. * Injection History: No corticosteroid injection to the affected elbow within the last 6 months. * Consent: Voluntary participation in the study Exclusion Criteria: * Elbow Pathology: Presence of elbow problems other than lateral epicondylitis (e.g., loose bodies, rheumatoid nodules). * Surgical History: History of previous surgery on the affected elbow joint. * Structural Damage: Presence of tendon rupture. * Consent: Unwillingness to continue treatment or participate. * Spinal Pathology: Cervical root pathology (cervical radiculopathy). * Neuropathy: Diagnosed upper extremity entrapment neuropathy. * Neurological Status: Presence of neurological impairment or deficits. * Recent Injections: History of injection therapy to the elbow within the last 6 months. * Recent Therapy: History of physical therapy for the elbow region within the last 6 months. * Pregnancy: Pregnant women. * Hematological: Presence of coagulation or bleeding disorders. * Vascular: Presence of peripheral vasculopathy. * Pain Syndromes: Presence of Complex Regional Pain Syndrome (CRPS). * Oncology: History of malignancy. * Systemic Diseases: Presence of systemic inflammatory or autoimmune disorders (e.g., Rheumatoid Arthritis, SLE). * Trauma: History of direct trauma to the elbow. * Medication: Current use of medications that may affect pain levels or muscle strength (e.g., muscle relaxants, analgesics, gabapentinoids). * Local Infection: Presence of open wounds, infection, or signs of active inflammation in the elbow region. * Cooperation: Difficulty in cooperation or cognitive inability to follow instructions. * Enzyme Deficiency: Congenital Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ankara Bilkent City Hospital
RECRUITINGAnkara, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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